Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 3 (EIF4EBP3)

ACP21285

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Specifications

Cat.No	ACP21285	Target Name	EIF4EBP3
Target Synonyms	EIF4EBP3Eukaryotic translation initiation factor 4E-binding protein 3; 4E-BP3; eIF4E-binding protein 3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-100
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O60516

Background Information

Uniprot Id

O60516
Target Species

Human
Target Name

EIF4EBP3
Target Full Name

Eukaryotic translation initiation factor 4E-binding protein 3
Target Function

Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
Target Protein Families

EIF4E-binding protein family
Target Tissue Specificity

Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

EIF4EBP3Eukaryotic translation initiation factor 4E-binding protein 3; 4E-BP3; eIF4E-binding protein 3

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Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 3 (EIF4EBP3)

Specifications

Immunogen Information

Inquire Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 3 (EIF4EBP3) Now

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