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| Cat.No | ACP11917 | Target Name | FAAP24 |
|---|---|---|---|
| Target Synonyms | FAAP24; C19orf40Fanconi anemia core complex-associated protein 24; Fanconi anemia-associated protein of 24 kDa | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-215 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BTP7 |
|---|
Uniprot Id
Q9BTP7
Target Species
Human
Target Name
FAAP24
Target Full Name
Fanconi anemia core complex-associated protein 24
Target Function
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Target Subcellular Location
Nucleus.
Target Synonyms
FAAP24; C19orf40Fanconi anemia core complex-associated protein 24; Fanconi anemia-associated protein of 24 kDa
Target Background
FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).
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