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Recombinant Human Fat storage-inducing transmembrane protein 2 (FITM2), Truncated

ACP07976

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Specifications

Cat.No	ACP07976	Target Name	FITM2
Target Synonyms	FITM2; C20orf142; FIT2; Acyl-coenzyme A diphosphatase FITM2; Fat storage-inducing transmembrane protein 2; Fat-inducing protein 2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8N6M3

Background Information

Uniprot Id

Q8N6M3
Target Species

Human
Target Name

FITM2
Target Full Name

Acyl-coenzyme A diphosphatase FITM2
Target Function

Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates such as oleoyl-CoA/(9Z)-octadecenoyl-CoA and arachidonoyl-CoA/(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. Plays a role in the regulation of cell morphology and cytoskeletal organization
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

FIT family
Target Tissue Specificity

Widely expressed.
Target Synonyms

FITM2; C20orf142; FIT2; Acyl-coenzyme A diphosphatase FITM2; Fat storage-inducing transmembrane protein 2; Fat-inducing protein 2

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Recombinant Human Fat storage-inducing transmembrane protein 2 (FITM2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Fat storage-inducing transmembrane protein 2 (FITM2), Truncated Now

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