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| Cat.No | ACP00371 | Target Name | FIGNL1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 374-674aa | Mol Weight | 37.1 |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6PIW4 |
|---|
Uniprot Id
Q6PIW4
Target Species
Human
Target Name
FIGNL1
Target Full Name
Fidgetin-like protein 1
Target Function
Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation. May play a role in the control of male meiosis dynamic.
Target Subcellular Location
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) treatment (PubMed:23754376).
Target Protein Families
AAA ATPase family
Target Research Area
Cell Biology
Target Synonyms
FIGNL1Fidgetin-like protein 1; EC 3.6.4.-
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