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| Cat.No | ACP01270 | Target Name | FXR1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 123-358aa | Mol Weight | 27.4 kDa |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51114 |
|---|
Uniprot Id
P51114
Target Species
Human
Target Name
FXR1
Target Full Name
RNA-binding protein FXR1
Target Function
RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs.
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
FMR1 family
Target Tissue Specificity
Expressed in all tissues examined including heart, brain, kidney and testis.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Fragile X mental retardation autosomal homolog 1; Fragile X mental retardation syndrome related protein 1; Fragile X mental retardation syndrome-related protein 1; FXR1; FXR1_HUMAN; FXR1P; hFXR1p
Target Background
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
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