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| Cat.No | ACP19708 | Target Name | BBOX1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-387 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75936 |
|---|
Uniprot Id
O75936
Target Species
Human
Target Name
BBOX1
Target Full Name
Gamma-butyrobetaine dioxygenase
Target Function
Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Gamma-BBH/TMLD family
Target Tissue Specificity
Highly expressed in kidney; moderately expressed in liver; very low expression in brain.
Target Research Area
Metabolism
Target Synonyms
2-oxoglutarate dioxygenase; BBH; BBOX 1; BBOX; Bbox1; BODG_HUMAN; Butyrobetaine (gamma) 2 oxoglutarate dioxygenase (gamma butyrobetaine hydroxylase) 1; G BBH; Gamma BBH; Gamma butyrobetaine 2 oxoglutarate dioxygenase 1; Gamma butyrobetaine dioxygenase; Gamma butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine; Gamma-butyrobetaine dioxygenase; Gamma-butyrobetaine hydroxylase
Target Background
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
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