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| Cat.No | ACP20313 | Target Name | ZGLP1 |
|---|---|---|---|
| Target Synonyms | ZGLP1; GLP1; GATA-type zinc finger protein 1; GATA-like protein 1; GLP-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-271 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P0C6A0 |
|---|
Uniprot Id
P0C6A0
Target Species
Human
Target Name
ZGLP1
Target Full Name
GATA-type zinc finger protein 1
Target Function
Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independently of retinoic acid (RA). In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase
Target Subcellular Location
Nucleus.
Target Synonyms
ZGLP1; GLP1; GATA-type zinc finger protein 1; GATA-like protein 1; GLP-1
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