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Recombinant Human Glycine receptor subunit alpha-3 (GLRA3), Truncated

ACP05384

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05384 Target NameGLRA3
Target SynonymsGLRA 3; Glra3; GLRA3_HUMAN; Glycine receptor alpha 3 polypeptide; Glycine receptor alpha 3 subunit; Glycine receptor subunit alpha 3; Glycine receptor subunit alpha-3; Ligand gated ion channelFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO75311
Background Information
  • Uniprot Id

    O75311

  • Target Species

    Human

  • Target Name

    GLRA3

  • Target Full Name

    Glycine receptor subunit alpha-3

  • Target Function

    Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Contributes to increased pain perception in response to increased prostaglandin E2 levels. Plays a role in cellular responses to ethanol.

  • Target Subcellular Location

    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Cell junction, synapse. Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Ligand-gated ion channel (TC 1.A.9) family, Glycine receptor (TC 1.A.9.3) subfamily, GLRA3 sub-subfamily

  • Target Tissue Specificity

    Widely distributed throughout the central nervous system.

  • Target Synonyms

    GLRA 3; Glra3; GLRA3_HUMAN; Glycine receptor alpha 3 polypeptide; Glycine receptor alpha 3 subunit; Glycine receptor subunit alpha 3; Glycine receptor subunit alpha-3; Ligand gated ion channel

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