Recombinant Human HAUS augmin-like complex subunit 1 (HAUS1)

Uniprot Id

Q96CS2

Target Species

Human

Target Name

HAUS1

Target Full Name

HAUS augmin-like complex subunit 1

Target Function

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Target Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.

Target Protein Families

HAUS1 family

Target Tissue Specificity

Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver and heart. Weakly expressed in lung, brain and placenta.

Target Synonyms

Coiled coil domain containing 5 (spindle associated) ; Coiled coil domain containing protein 5; Coiled-coil domain-containing protein 5; Enhancer of invasion cluster; Enhancer of invasion-cluster; HAUS augmin-like complex subunit 1; HAUS1; HAUS1_HUMAN; HEI-C; HEIC; HsT1461

Target Background

HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).