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| Cat.No | ACP15715 | Target Name | HAUS6 |
|---|---|---|---|
| Target Synonyms | HAUS6; DGT6; FAM29A; KIAA1574HAUS augmin-like complex subunit 6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z4H7 |
|---|
Uniprot Id
Q7Z4H7
Target Species
Human
Target Name
HAUS6
Target Full Name
HAUS augmin-like complex subunit 6
Target Function
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Protein Families
HAUS6 family
Target Synonyms
HAUS6; DGT6; FAM29A; KIAA1574HAUS augmin-like complex subunit 6
Target Background
The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
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