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This premium-grade Recombinant Human HBG2 is a powerful tool for researchers in the cardiovascular field. Hemoglobin subunit gamma-2, also known as gamma-2-globin, plays a crucial role in fetal oxygen transport during early development. Our recombinant protein is designed to support your experimental endeavors with exceptional performance and reliability. Recombinant Human HBG2 is expressed in E.coli, featuring the full length of the mature protein covering the expression region from 2-147 amino acids. The protein is N-terminal 6xHis-tagged and C-terminal Myc-tagged, facilitating straightforward purification and detection protocols. With a purity greater than 85% as determined by SDS-PAGE, this reagent ensures consistent performance and high quality for your research applications. Available in both liquid and lyophilized powder forms, Recombinant Human HBG2 is designed to accommodate your specific research requirements.
This premium-grade Recombinant Human HBG2 is a powerful tool for researchers in the cardiovascular field. Hemoglobin subunit gamma-2, also known as gamma-2-globin, plays a crucial role in fetal oxygen transport during early development. Our recombinant protein is designed to support your experimental endeavors with exceptional performance and reliability.
Recombinant Human HBG2 is expressed in E.coli, featuring the full length of the mature protein covering the expression region from 2-147 amino acids. The protein is N-terminal 6xHis-tagged and C-terminal Myc-tagged, facilitating straightforward purification and detection protocols. With a purity greater than 85% as determined by SDS-PAGE, this reagent ensures consistent performance and high quality for your research applications. Available in both liquid and lyophilized powder forms, Recombinant Human HBG2 is designed to accommodate your specific research requirements.
| Cat.No | ACP05247 | Target Name | HBG2 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 2-147aa | Mol Weight | 23.0 kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P69892 |
|---|
Uniprot Id
P69892
Target Species
Human
Target Name
HBG2
Target Full Name
Hemoglobin subunit gamma-2
Target Function
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Target Involvement
Cyanosis transient neonatal (TNCY)
Target Protein Families
Globin family
Target Tissue Specificity
Red blood cells.
Target Research Area
Cardiovascular
Target Synonyms
Abnormal hemoglobin; FLJ76540; G gamma globin; Gamma 2 globin; Gamma-2-globin; Hb F Ggamma; HBG 2; HBG2; HBG2_HUMAN; Hemoglobin gamma 2 chain; Hemoglobin gamma G; Hemoglobin gamma G chain; Hemoglobin gamma-2 chain; Hemoglobin gamma-G chain; Hemoglobin subunit gamma 2; Hemoglobin subunit gamma-2; Methemoglobin; OTTHUMP00000069638
Target Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
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