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Recombinant Human HERV-K_1q23.3 provirus ancestral Env polyprotein, Truncated

ACP08628

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP08628 Target NameERVK-18
Target Synonyms2 22 envelope protein; IDDMK1, 2 22 superantigenFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO42043
Background Information
  • Uniprot Id

    O42043

  • Target Species

    Human

  • Target Name

    ERVK-18

  • Target Full Name

    Endogenous retrovirus group K member 18 Env polyprotein

  • Target Function

    Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This envelope protein has superantigenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.

  • Target Subcellular Location

    [Transmembrane protein]: Cell membrane; Single-pass type I membrane protein.; [Surface protein]: Cell membrane; Peripheral membrane protein.; [Endogenous retrovirus group K member 18 Env polyprotein]: Virion.

  • Target Protein Families

    Beta type-B retroviral envelope protein family, HERV class-II K(HML-2) env subfamily

  • Target Tissue Specificity

    Expressed at higher level in the thymus. Expressed at lower level in peripheral blood lymphocytes.

  • Target Synonyms

    ERVK-18; Endogenous retrovirus group K member 18 Env polyprotein; Envelope polyprotein; HERV-K(C1a envelope protein; HERV-K110 envelope protein; HERV-K18 envelope protein; HERV-K18 superantigen; HERV-K_1q23.3 provirus ancestral Env polyprotein; IDDMK1,2 22 envelope protein; IDDMK1,2 22 superantigen

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