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| Cat.No | ACP21566 | Target Name | UTY |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14607 |
|---|
Uniprot Id
O14607
Target Species
Human
Target Name
UTY
Target Full Name
Histone demethylase UTY
Target Function
Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.
Target Subcellular Location
Nucleus.
Target Protein Families
UTX family
Target Synonyms
Histone demethylase UTY; Ubiquitously transcribed TPR protein on the Y chromosome; Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein; Ubiquitously-transcribed TPR protein on the Y chromosome; Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein; UTY; UTY_HUMAN
Target Background
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined.
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