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Recombinant Human Interferon regulatory factor 2-binding protein-like (IRF2BPL)

ACP10367

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10367 Target NameIRF2BPL
Target SynonymsIRF2BPL; C14orf4; EAP1; KIAA1865; My039; Probable E3 ubiquitin-protein ligase IRF2BPL; EC 2.3.2.27; Enhanced at puberty protein 1; Interferon regulatory factor 2-binding protein-likeFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-796
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9H1B7
Background Information
  • Uniprot Id

    Q9H1B7

  • Target Species

    Human

  • Target Name

    IRF2BPL

  • Target Full Name

    Probable E3 ubiquitin-protein ligase IRF2BPL

  • Target Function

    Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway. Probably plays a role in the development of the central nervous system and in neuronal maintenance (Probable). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    IRF2BP family

  • Target Tissue Specificity

    Highly expressed in the heart, moderately in skeletal muscle and pancreas, and weakly in brain, kidney, liver, testis, thyroid gland and lymphocytes.

  • Target Synonyms

    IRF2BPL; C14orf4; EAP1; KIAA1865; My039; Probable E3 ubiquitin-protein ligase IRF2BPL; EC 2.3.2.27; Enhanced at puberty protein 1; Interferon regulatory factor 2-binding protein-like

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