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| Cat.No | ACP24655 | Target Name | IRX3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-501 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P78415 |
|---|
Uniprot Id
P78415
Target Species
Human
Target Name
IRX3
Target Full Name
Iroquois-class homeodomain protein IRX-3
Target Function
Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Acts as a regulator of energy metabolism.
Target Subcellular Location
Nucleus.
Target Protein Families
TALE/IRO homeobox family
Target Synonyms
AI894186; Homeodomain protein IRXB1; Iroquois class homeodomain protein IRX 1; Iroquois homeobox 3; Iroquois homeobox protein 3; Iroquois-class homeodomain protein irx-3; IRX 1; irx3; IRX3_HUMAN; IRXB1
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