Recombinant Human Iroquois-class homeodomain protein IRX-5 (IRX5)

ACP24619

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Specifications

Cat.No	ACP24619	Target Name	IRX5
Target Synonyms	Homeodomain protein IRX-2A; Homeodomain protein IRXB2; Iroquois homeobox protein 5; Iroquois-class homeodomain protein IRX-5; IRX2A; Irx5; IRX5_HUMAN; IRXB2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-483
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P78411

Background Information

Uniprot Id

P78411
Target Species

Human
Target Name

IRX5
Target Full Name

Iroquois-class homeodomain protein IRX-5
Target Function

Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina. Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development. Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12.
Target Involvement

Hamamy syndrome (HMMS)
Target Subcellular Location

Nucleus.
Target Protein Families

TALE/IRO homeobox family
Target Synonyms

Homeodomain protein IRX-2A; Homeodomain protein IRXB2; Iroquois homeobox protein 5; Iroquois-class homeodomain protein IRX-5; IRX2A; Irx5; IRX5_HUMAN; IRXB2

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Recombinant Human Iroquois-class homeodomain protein IRX-5 (IRX5)

Specifications

Immunogen Information

Inquire Recombinant Human Iroquois-class homeodomain protein IRX-5 (IRX5) Now

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