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| Cat.No | ACP15916 | Target Name | KRT80 |
|---|---|---|---|
| Target Synonyms | CK 80; CK-80; CK80; Cytokeratin 80; Cytokeratin-80; K 80; K2C80_HUMAN; K80; KB20; Keratin 80; Keratin; Keratin-80; KRT 80; Krt80; type II cytoskeletal 80; Type II keratin; Type-II keratin Kb20 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-452 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6KB66 |
|---|
Uniprot Id
Q6KB66
Target Species
Human
Target Name
KRT80
Target Full Name
Keratin, type II cytoskeletal 80
Target Synonyms
CK 80; CK-80; CK80; Cytokeratin 80; Cytokeratin-80; K 80; K2C80_HUMAN; K80; KB20; Keratin 80; Keratin; Keratin-80; KRT 80; Krt80; type II cytoskeletal 80; Type II keratin; Type-II keratin Kb20
Target Background
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.
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