Recombinant Human Kinesin-like protein KIF16B (KIF16B), Truncated

Uniprot Id

Q96L93

Target Species

Human

Target Name

KIF16B

Target Full Name

Kinesin-like protein KIF16B

Target Function

Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.

Target Subcellular Location

Cytoplasm, cytoskeleton. Early endosome membrane. Cytoplasm. Cytoplasm, cytoskeleton, spindle.

Target Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

Target Tissue Specificity

Primarily expressed in brain. Also present in kidney, liver, intestine, placenta, leukocytes, heart and skeletal muscle (at protein level).

Target Synonyms

KIF16B; C20orf23; KIAA1590; SNX23Kinesin-like protein KIF16B; Sorting nexin-23

Target Background

The protein encoded by this gene is a kinesin-like protein that may be involved in intracellular trafficking. Three transcript variants encoding different isoforms have been found for this gene.