Recombinant Human Left-right determination factor 1 (LEFTY1)

ACP20556

Number

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Specifications

Cat.No	ACP20556	Target Name	LEFTY1
Target Synonyms	LEFTY1; LEFTB; LEFTYB; UNQ278/PRO317Left-right determination factor 1; Left-right determination factor B; Protein lefty-1; Protein lefty-B	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	77-366
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O75610

Background Information

Uniprot Id

O75610
Target Species

Human
Target Name

LEFTY1
Target Full Name

Left-right determination factor 1
Target Function

Required for left-right axis determination as a regulator of LEFTY2 and NODAL.
Target Subcellular Location

Secreted.
Target Protein Families

TGF-beta family
Target Synonyms

LEFTY1; LEFTB; LEFTYB; UNQ278/PRO317Left-right determination factor 1; Left-right determination factor B; Protein lefty-1; Protein lefty-B
Target Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene.

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Recombinant Human Left-right determination factor 1 (LEFTY1)

Specifications

Immunogen Information

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