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| Cat.No | ACP06762 | Target Name | LEPROT |
|---|---|---|---|
| Target Synonyms | LEPROT; LEPR; OBR; Leptin receptor gene-related protein; Endospanin-1; Leptin receptor overlapping transcript protein; OB-R gene-related protein; OB-RGRP | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O15243 |
|---|
Uniprot Id
O15243
Target Species
Human
Target Name
LEPROT
Target Full Name
Leptin receptor gene-related protein
Target Function
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
Target Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane.
Target Protein Families
OB-RGRP/VPS55 family
Target Tissue Specificity
Expressed at the highest levels in heart and placenta and at a lesser extent in lung, liver, skeletal muscle, kidney and pancreas.
Target Synonyms
LEPROT; LEPR; OBR; Leptin receptor gene-related protein; Endospanin-1; Leptin receptor overlapping transcript protein; OB-R gene-related protein; OB-RGRP
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