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| Cat.No | ACP04515 | Target Name | LRBA |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-251aa | Mol Weight | 31.6kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P50851 |
|---|
Uniprot Id
P50851
Target Species
Human
Target Name
LRBA
Target Full Name
Lipopolysaccharide-responsive and beige-like anchor protein
Target Function
May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules.
Target Involvement
Immunodeficiency, common variable, 8, with autoimmunity (CVID8)
Target Subcellular Location
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Lysosome.
Target Tissue Specificity
Ubiquitous.
Target Research Area
Signal Transduction
Target Synonyms
Beige-like protein; BGL; C80285; CDC4-like protein; CDC4L; CVID8; D3Ertd775e; Lab300; LBA; Lipopolysaccharide-responsive and beige-like anchor protein; LPS-responsive vesicle trafficking beach and anchor containing; Lrba; LRBA_HUMAN; Vesicle trafficking beach and anchor containing
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