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| Cat.No | ACP00856 | Target Name | LIAS |
|---|---|---|---|
| Target Synonyms | (Lipoate synthase)(LS)(Lip-syn)(Lipoic acid synthase) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 28-372aa |
| Mol Weight | 45.8 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43766 |
|---|
Uniprot Id
O43766
Target Species
Human
Target Name
LIAS
Target Full Name
Lipoyl synthase, mitochondrial
Target Function
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
Target Involvement
Hyperglycinemia, lactic acidosis, and seizures (HGCLAS)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Radical SAM superfamily, Lipoyl synthase family
Target Research Area
Metabolism
Target Synonyms
LIAS; LAS; HUSSY-01Lipoyl synthase; mitochondrial; EC 2.8.1.8; Lipoate synthase; LS; Lip-syn; Lipoic acid synthase
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