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Recombinant Human Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A), Truncated

ACP00338

Number
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Specifications


Cat.No ACP00338 Target NameFCGR2A
Target SynonymsIgG Fc receptor II-a;CDw32;Fc-gamma RII-a;Fc-gamma-RIIa;FcRII-a;CD antigen CD32FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range34-217aa
Mol Weight24.5 kDaProtein LengthPartial
PurityGreater than 95% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP12318
Background Information
  • Uniprot Id

    P12318

  • Target Species

    Human

  • Target Name

    FCGR2A

  • Target Full Name

    Low affinity immunoglobulin gamma Fc region receptor II-a

  • Target Function

    Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Found on monocytes, neutrophils and eosinophil platelets.

  • Target Research Area

    Immunology

  • Target Synonyms

    FCGR2A; CD32; FCG2; FCGR2A1; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD antigen CD32

  • Target Background

    This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

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