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| Cat.No | ACP02149 | Target Name | MAN1A2 |
|---|---|---|---|
| Target Synonyms | 2-mannosidase IB, 2-mannosidase IB; Alpha-1, Mannosidase alpha class 1A member 2;Processing alpha-1 | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-641aa |
| Mol Weight | 74.5 | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60476 |
|---|
Uniprot Id
O60476
Target Species
Human
Target Name
MAN1A2
Target Full Name
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
Target Function
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyl hydrolase 47 family
Target Tissue Specificity
Highest levels of expression in placenta and testis.
Target Research Area
Metabolism
Target Synonyms
MAN1A2; MAN1B; Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Mannosidase alpha class 1A member 2; Processing alpha-1,2-mannosidase IB; Alpha-1,2-mannosidase IB
Target Background
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.
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