Recombinant Human Mediator of RNA polymerase II transcription subunit 16 (MED16), Truncated

Uniprot Id

Q9Y2X0

Target Species

Human

Target Name

MED16

Target Full Name

Mediator of RNA polymerase II transcription subunit 16

Target Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Target Subcellular Location

Nucleus.

Target Protein Families

Mediator complex subunit 16 family

Target Synonyms

DRIP 92 ; DRIP92; MED 16; MED16; MED16_HUMAN; Mediator complex subunit 16; Mediator of RNA polymerase II transcription subunit 16; THRAP 5; Thyroid hormone receptor associated protein 5; Thyroid hormone receptor associated protein 95 kD subunit; Thyroid hormone receptor associated protein complex 95 kDa component; Thyroid hormone receptor-associated protein 5; Thyroid hormone receptor-associated protein complex 95 kDa component; Trap 95; Trap95; Vitamin D3 receptor interacting protein complex component ; Vitamin D3 receptor-interacting protein complex 92 kDa component