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Recombinant Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI2), Truncated

ACP15570

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15570 Target NameMAGI2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ86UL8
Background Information
  • Uniprot Id

    Q86UL8

  • Target Species

    Human

  • Target Name

    MAGI2

  • Target Full Name

    Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

  • Target Function

    Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.

  • Target Involvement

    Nephrotic syndrome 15 (NPHS15)

  • Target Subcellular Location

    Cytoplasm. Late endosome. Cell junction, synapse, synaptosome. Cell membrane; Peripheral membrane protein.

  • Target Protein Families

    MAGUK family

  • Target Tissue Specificity

    Specifically expressed in brain.

  • Target Synonyms

    Activin receptor interacting protein 1; Acvri1 ; Acvrinp1; ACVRIP1; AIP 1; Aip-1; ARIP1; Atrophin 1 interacting protein 1; Atrophin 1 interacting protein A; Atrophin-1-interacting protein 1; Atrophin-1-interacting protein A; KIAA0705; MAGI-2; MAGI2; MAGI2_HUMAN; Membrane associated guanylate kinase 2; Membrane associated guanylate kinase inverted 2; Membrane associated guanylate kinase WW and PDZ domain containing 2; Membrane associated guanylate kinase WW and PDZ domain containing protein 2; Membrane-associated guanylate kinase; Membrane-associated guanylate kinase inverted 2; S SCAM ; SSCAM; WW and PDZ domain-containing protein 2

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