Recombinant Human Membrane-spanning 4-domains subfamily A member 7 (MS4A7), Truncated

Uniprot Id

Q9GZW8

Target Species

Human

Target Name

MS4A7

Target Full Name

Membrane-spanning 4-domains subfamily A member 7

Target Function

May be involved in signal transduction as a component of a multimeric receptor complex.

Target Subcellular Location

Membrane; Multi-pass membrane protein.

Target Protein Families

MS4A family

Target Tissue Specificity

Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detect

Target Synonyms

MS4A7; 4SPAN2; CD20L4; CFFM4; Membrane-spanning 4-domains subfamily A member 7; CD20 antigen-like 4; CD20/FC-epsilon-RI-beta family member 4; Four-span transmembrane protein 2

Target Background

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.