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Recombinant Human Metalloreductase STEAP1 (STEAP1)-VLPs

ACP01733

Number
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Specifications


Cat.No ACP01733 Target NameSTEAP1
Target SynonymsSix-transmembrane epithelial antigen of prostate 1FormLiquid or Lyophilized powder
Expression SystemMammalian cellExpression Range1-339aa
Mol Weight41.2 kDaProtein LengthFull length
PurityThe purity information is not available for VLPs proteins.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UHE8
Background Information
  • Uniprot Id

    Q9UHE8

  • Target Species

    Human

  • Target Name

    STEAP1

  • Target Full Name

    STEAP1 protein

  • Target Function

    Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.

  • Target Subcellular Location

    Endosome membrane; Multi-pass membrane protein.

  • Target Protein Families

    STEAP family

  • Target Tissue Specificity

    Ubiquitously expressed. Highly expressed in prostate tumors.

  • Target Research Area

    Epigenetics and Nuclear Signaling, Transport

  • Target Synonyms

    STEAP1; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1

  • Target Background

    This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.

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