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| Cat.No | ACP06021 | Target Name | SLC47A2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86VL8 |
|---|
Uniprot Id
Q86VL8
Target Species
Human
Target Name
SLC47A2
Target Full Name
Multidrug and toxin extrusion protein 2
Target Function
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules.
Target Protein Families
Multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family
Target Tissue Specificity
Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain.
Target Synonyms
H(+)/organic cation antiporter kidney-specific; H+/organic cation antiporter; hMATE-2; Kidney-specific H(+)/organic cation antiporter; MATE-2; MATE2 B; MATE2 K; MATE2K; Multidrug and toxin extrusion 2; Multidrug and toxin extrusion protein 2; S47A2_HUMAN; SLC47A2; Solute carrier family 47 member 2
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