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| Cat.No | ACP19686 | Target Name | CAVIN4 |
|---|---|---|---|
| Target Synonyms | murC; MURC_HUMAN; Muscle-related coiled-coil protein; Muscle-restricted coiled-coil protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-364 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5BKX8 |
|---|
Uniprot Id
Q5BKX8
Target Species
Human
Target Name
CAVIN4
Target Full Name
Caveolae-associated protein 4
Target Function
Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation. Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes. Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.
Target Subcellular Location
Cytoplasm, myofibril, sarcomere. Cytoplasm. Cytoplasm, cytosol. Cell membrane, sarcolemma. Membrane, caveola. Cell membrane.
Target Protein Families
CAVIN family
Target Synonyms
murC; MURC_HUMAN; Muscle-related coiled-coil protein; Muscle-restricted coiled-coil protein
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