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Recombinant Human N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB), Truncated

ACP08342

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP08342	Target Name	GNPTAB
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q3T906

Background Information

Uniprot Id

Q3T906
Target Species

Human
Target Name

GNPTAB
Target Full Name

N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
Target Function

Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment.
Target Involvement

Mucolipidosis type II (MLII); Mucolipidosis type III complementation group A (MLIIIA)
Target Subcellular Location

[N-acetylglucosamine-1-phosphotransferase subunit alpha]: Golgi apparatus membrane; Single-pass type I membrane protein.; [N-acetylglucosamine-1-phosphotransferase subunit beta]: Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families

Stealth family
Target Tissue Specificity

Expressed in the heart, whole brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Target Synonyms

GNPTAB; GNPTA; KIAA1208; N-acetylglucosamine-1-phosphotransferase subunits alpha/beta; GlcNAc-1-phosphotransferase subunits alpha/beta; Stealth protein GNPTAB; UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

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Recombinant Human N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB), Truncated Now

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