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| Cat.No | ACP18425 | Target Name | ME3 |
|---|---|---|---|
| Target Synonyms | ME3NADP-dependent malic enzyme; mitochondrial; NADP-ME; EC 1.1.1.40; Malic enzyme 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16798 |
|---|
Uniprot Id
Q16798
Target Species
Human
Target Name
ME3
Target Full Name
NADP-dependent malic enzyme, mitochondrial
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Malic enzymes family
Target Tissue Specificity
Expressed predominantly in organs with a low-division rate.
Target Research Area
others
Target Synonyms
ME3NADP-dependent malic enzyme; mitochondrial; NADP-ME; EC 1.1.1.40; Malic enzyme 3
Target Background
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
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