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Recombinant Human Nance-Horan syndrome protein (NHS), Truncated

ACP16335

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16335 Target NameNHS
Target SynonymsNHS; Nance-Horan syndrome protein; Congenital cataracts and dental anomalies proteinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6T4R5
Background Information
  • Uniprot Id

    Q6T4R5

  • Target Species

    Human

  • Target Name

    NHS

  • Target Full Name

    Actin remodeling regulator NHS

  • Target Function

    May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development.

  • Target Involvement

    Nance-Horan syndrome (NHS); Cataract 40 (CTRCT40)

  • Target Subcellular Location

    [Isoform 1]: Apical cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell junction, tight junction. Cell junction, focal adhesion. Note=Colocalizes with the tight junction protein TJP1 in epithelial cells. Localizes to the leading edge of lamellipodia in motile cells.; [Isoform 3]: Cytoplasm.

  • Target Protein Families

    NHS family

  • Target Tissue Specificity

    Detected at low levels in all tissues analyzed. Detected in fetal and adult brain, lens, retina, retinal pigment epithelium, placenta, lymphocytes and fibroblasts. Levels in retinal pigment epithelium, placenta, lymphocytes, and fibroblasts are very low.

  • Target Synonyms

    NHS; Nance-Horan syndrome protein; Congenital cataracts and dental anomalies protein

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