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| Cat.No | ACP16335 | Target Name | NHS |
|---|---|---|---|
| Target Synonyms | NHS; Nance-Horan syndrome protein; Congenital cataracts and dental anomalies protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6T4R5 |
|---|
Uniprot Id
Q6T4R5
Target Species
Human
Target Name
NHS
Target Full Name
Actin remodeling regulator NHS
Target Function
May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development.
Target Involvement
Nance-Horan syndrome (NHS); Cataract 40 (CTRCT40)
Target Subcellular Location
[Isoform 1]: Apical cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell junction, tight junction. Cell junction, focal adhesion. Note=Colocalizes with the tight junction protein TJP1 in epithelial cells. Localizes to the leading edge of lamellipodia in motile cells.; [Isoform 3]: Cytoplasm.
Target Protein Families
NHS family
Target Tissue Specificity
Detected at low levels in all tissues analyzed. Detected in fetal and adult brain, lens, retina, retinal pigment epithelium, placenta, lymphocytes and fibroblasts. Levels in retinal pigment epithelium, placenta, lymphocytes, and fibroblasts are very low.
Target Synonyms
NHS; Nance-Horan syndrome protein; Congenital cataracts and dental anomalies protein
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