Recombinant Human Neuropilin and tolloid-like protein 1 (NETO1), Truncated

Uniprot Id

Q8TDF5

Target Species

Human

Target Name

NETO1

Target Full Name

Neuropilin and tolloid-like protein 1

Target Function

Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.

Target Subcellular Location

[Isoform 2]: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 1]: Secreted.

Target Tissue Specificity

Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain.

Target Synonyms

AI851453; BCTL1; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 ; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1; BTCL1; C130005O10Rik; FLJ41325; Neto1; NETO1_HUMAN; Neuropilin and tolloid like 1; Neuropilin and tolloid-like protein 1; RGD1566269