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Recombinant Human Nucleolar GTP-binding protein 2 (GNL2)

ACP18157

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Specifications

Cat.No	ACP18157	Target Name	GNL2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-731	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q13823

Background Information

Uniprot Id

Q13823
Target Species

Human
Target Name

GNL2
Target Full Name

Nucleolar GTP-binding protein 2
Target Function

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
Target Subcellular Location

Nucleus, nucleolus.
Target Protein Families

TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily
Target Tissue Specificity

Widely expressed, with the highest expression level in testis.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

Autoantigen NGP-1; Autoantigen NGP1; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein; FLJ40906; GNL2; Guanine nucleotide binding protein-like 2 (nucleolar); HUMAUANTIG; NGP1; NOG2_HUMAN; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen; nucleolar G-protein gene 1; Nucleolar GTP binding protein 2; Nucleolar GTP-binding protein 2; Nucleolar GTPase
Target Background

Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus.

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Recombinant Human Nucleolar GTP-binding protein 2 (GNL2)

Specifications

Immunogen Information

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