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| Cat.No | ACP20518 | Target Name | OAZ2 |
|---|---|---|---|
| Target Synonyms | OAZ2; Ornithine decarboxylase antizyme 2; AZ2; ODC-Az 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-189 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95190 |
|---|
Uniprot Id
O95190
Target Species
Human
Target Name
OAZ2
Target Full Name
Ornithine decarboxylase antizyme 2
Target Function
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.
Target Subcellular Location
Nucleus.
Target Protein Families
ODC antizyme family
Target Synonyms
OAZ2; Ornithine decarboxylase antizyme 2; AZ2; ODC-Az 2
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