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Recombinant Human Phosphatidylinositol-glycan biosynthesis class X protein (PIGX), Truncated

ACP04330

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Specifications

Cat.No	ACP04330	Target Name	PIGX
Target Synonyms	GPI mannosyltransferase subunit; Phosphatidylinositol glycan class X; Phosphatidylinositol-glycan biosynthesis class X protein; PIG-X; Pigx; PIGX_HUMAN	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	42-230aa
Mol Weight	37.8kDa	Protein Length	Partial
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8TBF5

Background Information

Uniprot Id

Q8TBF5
Target Species

Human
Target Name

PIGX
Target Full Name

Phosphatidylinositol-glycan biosynthesis class X protein
Target Function

Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM.
Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Target Protein Families

PIGX family
Target Research Area

Metabolism
Target Synonyms

GPI mannosyltransferase subunit; Phosphatidylinositol glycan class X; Phosphatidylinositol-glycan biosynthesis class X protein; PIG-X; Pigx; PIGX_HUMAN
Target Background

This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants.

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Recombinant Human Phosphatidylinositol-glycan biosynthesis class X protein (PIGX), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Phosphatidylinositol-glycan biosynthesis class X protein (PIGX), Truncated Now

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