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Recombinant Human Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1), Truncated

ACP16297

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16297 Target NamePIK3AP1
Target SynonymsPIK3AP1; BCAPPhosphoinositide 3-kinase adapter protein 1; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6ZUJ8
Background Information
  • Uniprot Id

    Q6ZUJ8

  • Target Species

    Human

  • Target Name

    PIK3AP1

  • Target Full Name

    Phosphoinositide 3-kinase adapter protein 1

  • Target Function

    Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Peripheral membrane protein.

  • Target Tissue Specificity

    Expressed in natural killer (NK) cells.

  • Target Synonyms

    PIK3AP1; BCAPPhosphoinositide 3-kinase adapter protein 1; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1

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