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Recombinant Human Pirin (PIR)

ACP21674

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21674 Target NamePIR
Target Synonyms3-dioxygenase PIR; Iron binding nuclear protein; Pir; PIR_HUMAN; Pirin; Probable quercetin 2; probable quercetin 2, 3-dioxygenase PIR; Probable quercetinaseFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-290
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO00625
Background Information
  • Uniprot Id

    O00625

  • Target Species

    Human

  • Target Name

    PIR

  • Target Full Name

    Pirin

  • Target Function

    Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro).

  • Target Subcellular Location

    Nucleus. Cytoplasm.

  • Target Protein Families

    Pirin family

  • Target Tissue Specificity

    Highly expressed in a subset of melanomas. Detected at very low levels in most tissues (at protein level). Expressed in all tissues, with highest level of expression in heart and liver.

  • Target Synonyms

    3-dioxygenase PIR; Iron binding nuclear protein; Pir; PIR_HUMAN; Pirin; Probable quercetin 2; probable quercetin 2,3-dioxygenase PIR; Probable quercetinase

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