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| Cat.No | ACP03168 | Target Name | PLEKHF2 |
|---|---|---|---|
| Target Synonyms | family F (with FYVE domain) member 2; pleckstrin homology domain containing | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-249aa |
| Mol Weight | 54.8kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H8W4 |
|---|
Uniprot Id
Q9H8W4
Target Species
Human
Target Name
PLEKHF2
Target Full Name
Pleckstrin homology domain-containing family F member 2
Target Function
May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
Target Subcellular Location
Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum.
Target Tissue Specificity
Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells.
Target Research Area
Cell Biology
Target Synonyms
110070J07Rik; AA673237; FLJ13187; PH and FYVE domain containing protein 2; PH and FYVE domain-containing protein 2; PH domain containing family F member 2; PH domain-containing family F member 2; Phafin 2; Phafin-2; PHAFIN2; PKHF2_HUMAN; pleckstrin homology domain containing, family F (with FYVE domain) member 2; pleckstrin homology domain containing, family F (with FYVE domain) member2 ; Pleckstrin homology domain-containing family F member 2; Plekhf2; ZFYVE18; Zinc finger FYVE domain containing protein 18 ; Zinc finger FYVE domain-containing protein 18
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