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| Cat.No | ACP12253 | Target Name | PLEKHG2 |
|---|---|---|---|
| Target Synonyms | PLEKHG2; Pleckstrin homology domain-containing family G member 2; PH domain-containing family G member 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H7P9 |
|---|
Uniprot Id
Q9H7P9
Target Species
Human
Target Name
PLEKHG2
Target Full Name
Pleckstrin homology domain-containing family G member 2
Target Function
May be a transforming oncogene with exchange activity for CDC42. May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein). Involved in the regulation of actin polymerization.
Target Involvement
Leukodystrophy and acquired microcephaly with or without dystonia (LDAMD)
Target Synonyms
PLEKHG2; Pleckstrin homology domain-containing family G member 2; PH domain-containing family G member 2
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