Home Products Recombinant Human Pleckstrin homology domain-containing family G member 6 (PLEKHG6)

Recombinant Human Pleckstrin homology domain-containing family G member 6 (PLEKHG6)

ACP17516

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Specifications

Cat.No	ACP17516	Target Name	PLEKHG6
Target Synonyms	PLEKHG6; Pleckstrin homology domain-containing family G member 6; PH domain-containing family G member 6; Myosin-interacting guanine nucleotide exchange factor; MyoGEF	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-790
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q3KR16

Background Information

Uniprot Id

Q3KR16
Target Species

Human
Target Name

PLEKHG6
Target Full Name

Pleckstrin homology domain-containing family G member 6
Target Function

Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Target Subcellular Location

Cell projection, microvillus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cleavage furrow.
Target Tissue Specificity

Highest expression in the placenta. Low levels in small intestine, lung, liver, kidney, thymus and heart.
Target Synonyms

PLEKHG6; Pleckstrin homology domain-containing family G member 6; PH domain-containing family G member 6; Myosin-interacting guanine nucleotide exchange factor; MyoGEF

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Recombinant Human Pleckstrin homology domain-containing family G member 6 (PLEKHG6)

Specifications

Immunogen Information

Inquire Recombinant Human Pleckstrin homology domain-containing family G member 6 (PLEKHG6) Now

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