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| Cat.No | ACP14865 | Target Name | PNLDC1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NA58 |
|---|
Uniprot Id
Q8NA58
Target Species
Human
Target Name
PNLDC1
Target Full Name
Poly(A)-specific ribonuclease PNLDC1
Target Function
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
CAF1 family
Target Synonyms
oly(A)-specific ribonuclease PARN-like domain-containing protein 1; PNDC1_HUMAN; PNLDC1; poly(A)-specific ribonuclease (PARN)-like domain containing 1; Poly(A)-specific ribonuclease PARN-like domain-containing protein 1; RP1-195P10.1
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