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Recombinant Human Potassium channel subfamily U member 1 (KCNU1), Truncated

ACP05426

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05426 Target NameKCNU1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDA8MYU2
Background Information
  • Uniprot Id

    A8MYU2

  • Target Species

    Human

  • Target Name

    KCNU1

  • Target Full Name

    Potassium channel subfamily U member 1

  • Target Function

    Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa5.1/KCNU1 sub-subfamily

  • Target Tissue Specificity

    Testis-specific.

  • Target Synonyms

    subfamily M subunit alpha-3; Calcium activated potassium channel subfamily M subunit alpha 3; Calcium activated potassium channel subunit alpha 3; Calcium-activated potassium channel; Calcium-activated potassium channel subunit alpha-3; KCa5; KCa5.1; Kcnma3; KCNMC1; KCNU 1; KCNU1; KCNU1_HUMAN; Potassium channel subfamily U member 1; Slo3; Slowpoke homolog 3

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