Home Products Recombinant Human Potassium voltage-gated channel subfamily KQT member 4 (KCNQ4), Truncated

Recombinant Human Potassium voltage-gated channel subfamily KQT member 4 (KCNQ4), Truncated

ACP06896

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Specifications

Cat.No	ACP06896	Target Name	KCNQ4
Target Synonyms	KCNQ4; Potassium voltage-gated channel subfamily KQT member 4; KQT-like 4; Potassium channel subunit alpha KvLQT4; Voltage-gated potassium channel subunit Kv7.4	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P56696

Background Information

Uniprot Id

P56696
Target Species

Human
Target Name

KCNQ4
Target Full Name

Potassium voltage-gated channel subfamily KQT member 4
Target Function

Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.
Target Involvement

Deafness, autosomal dominant, 2A (DFNA2A)
Target Subcellular Location

Basal cell membrane; Multi-pass membrane protein.
Target Protein Families

Potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.4/KCNQ4 sub-subfamily
Target Tissue Specificity

Expressed in the outer, but not the inner, sensory hair cells of the cochlea. Slightly expressed in heart, brain and skeletal muscle.
Target Synonyms

KCNQ4; Potassium voltage-gated channel subfamily KQT member 4; KQT-like 4; Potassium channel subunit alpha KvLQT4; Voltage-gated potassium channel subunit Kv7.4

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Recombinant Human Potassium voltage-gated channel subfamily KQT member 4 (KCNQ4), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Potassium voltage-gated channel subfamily KQT member 4 (KCNQ4), Truncated Now

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