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Recombinant Human Probable histone-lysine N-methyltransferase PRDM7 (PRDM7)

ACP04981

Number
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Specifications


Cat.No ACP04981 Target NamePRDM7
Target SynonymsPRDM7; PFM4Probable histone-lysine N-methyltransferase PRDM7; EC 2.1.1.-; PR domain zinc finger protein 7; PR domain-containing protein 7FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range1-492aa
Mol Weight59.9 kDaProtein LengthFull length
PurityGreater than 85% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NQW5
Background Information
  • Uniprot Id

    Q9NQW5

  • Target Species

    Human

  • Target Name

    PRDM7

  • Target Full Name

    Histone-lysine N-methyltransferase PRDM7

  • Target Function

    Histone methyltransferase that selectively methylates 'Lys-4' of dimethylated histone H3 (H3K4me2) to produce trimethylated 'Lys-4' histone H3 (H3K4me3). May play a role in epigenetic regulation of gene expression by defining an active chromatin state.

  • Target Subcellular Location

    Nucleus. Chromosome.

  • Target Research Area

    Others

  • Target Synonyms

    PRDM7; PFM4Probable histone-lysine N-methyltransferase PRDM7; EC 2.1.1.-; PR domain zinc finger protein 7; PR domain-containing protein 7

  • Target Background

    This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase.

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