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| Cat.No | ACP14491 | Target Name | BRK1 |
|---|---|---|---|
| Target Synonyms | BRK1; C3orf10; HSPC300; MDS027; Protein BRICK1; BRK1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-75 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WUW1 |
|---|
Uniprot Id
Q8WUW1
Target Species
Human
Target Name
BRK1
Target Full Name
Protein BRICK1
Target Function
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
BRK1 family
Target Synonyms
BRK1; C3orf10; HSPC300; MDS027; Protein BRICK1; BRK1
Target Background
Enables identical protein binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction and positive regulation of cellular component organization. Located in extracellular exosome. Part of SCAR complex.
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