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| Cat.No | ACP04397 | Target Name | DGCR6L |
|---|---|---|---|
| Target Synonyms | DGC6L_HUMAN; DGCR6L; DiGeorge syndrome critical region 6-like protein; Protein DGCR6L | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-220aa |
| Mol Weight | 40.9kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BY27 |
|---|
Uniprot Id
Q9BY27
Target Species
Human
Target Name
DGCR6L
Target Full Name
Protein DGCR6L
Target Function
May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.
Target Subcellular Location
Nucleus. Note=Predominantly nuclear.
Target Protein Families
Gonadal family
Target Tissue Specificity
Widely expressed in fetal and adult tissues. Highest expression in liver, heart and skeletal muscle. Lower levels in pancreas and placenta. Weak expression in brain.
Target Research Area
Cell Biology
Target Synonyms
DGC6L_HUMAN; DGCR6L; DiGeorge syndrome critical region 6-like protein; Protein DGCR6L
Target Background
This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome.
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