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Recombinant Human Protein FAM35A (FAM35A), Truncated

ACP15565

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15565 Target NameFAM35A
Target SynonymsSHLD2; FAM35A; RINN2; Shieldin complex subunit 2; Protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; Shield complex subunit 2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ86V20
Background Information
  • Uniprot Id

    Q86V20

  • Target Species

    Human

  • Target Name

    FAM35A

  • Target Full Name

    Shieldin complex subunit 2

  • Target Function

    Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres.

  • Target Subcellular Location

    Nucleus. Chromosome.

  • Target Protein Families

    FAM35 family

  • Target Synonyms

    SHLD2; FAM35A; RINN2; Shieldin complex subunit 2; Protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; Shield complex subunit 2

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