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| Cat.No | ACP07565 | Target Name | TMBIM1 |
|---|---|---|---|
| Target Synonyms | TMBIM1; LFG3; RECS1; PP1201; PSEC0158; Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q969X1 |
|---|
Uniprot Id
Q969X1
Target Species
Human
Target Name
TMBIM1
Target Full Name
Protein lifeguard 3
Target Function
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Lysosome membrane. Endosome membrane.
Target Protein Families
BI1 family, LFG subfamily
Target Synonyms
TMBIM1; LFG3; RECS1; PP1201; PSEC0158; Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1
Target Background
Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi apparatus; endosome membrane; and lysosomal membrane.
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